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NJBMS - Volume 5, Issue 1, July - September 2014

Pages: 244-246

A RARE CASE OF GYNANDROBLASTOMA WITH JUVENILE GRANULOSA COMPONENT

Author: SRI VIDYA VVL, GAYATRI V.

Category: Pathology

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Abstract:

We report a case of a female aged 20yrs, with complaint of Amenorrhea for 7months, which started with oligomenorrheic cycle of 2-3days / 2-3months for 2yrs. Clinically, it presents clinically as an abdominal mass, associated with either virilizing or feminizing manifestations. Histopathological study of adnexeal mass revealed characteristic features of juvenile granulosa cell tumor, associated with sertoli-leydig cell component. The tumor consisted of substantial amount of granulosa cell elements and sertoli cell elements, with intermingled leydig cells. Immunohistochemistry revealed the tumor cells in both granulosa cell and sertolileydig cell elements were positive for vimentin. The prognosis depends on the individual tumor components. We report this case in viewof its rarity.

Keywords: Sertoli-leydig cell tumor, Juvenile granulosacell tumor, Gynandroblastoma.

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Editor in Chief of NJBMS Dr.Deepti Shastri, Professor and Head, Department of Anatomy, Academic Co-ordinator for Pre and Paraclinical Sciences, VMKV Medical College & Hospital, Salem.


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