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NJBMS - Volume 4, Issue 3, January - March 2014

Pages: 159-162

PREVALENCE OF CRYPTOSPORIDIAL DIARRHOEAS AMONG HUMAN IMMUNODEFICIENCY VIRUS PATIENTS

Author: G. KANNAN, R. SHANKAR, RAJESH

Category: Clinical Sciences

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Abstract:

Background: Crystosporidiosis is a major cause of diarrhoea in HIV infection in developing countries. AIDS and protein energy malnutrition are severly imparing the immune system, in such pateints cellular immunity is low and implies that cellular immunity is the major component in elimination the infection. Despite numerous clinical trials with several antimicrobial agents, no therapy has been shown to be curative for cryptosporidium.

Aim: To assess the Prevalance of Crptosporidial diarrhoeas among HIV postive patients.

Materials and Methods: A prospect cross sectional study was carried out in the department of Skin and STD of Vinayaka Mission Medical College Hospital, Salem for 3 years from 2009‑2012. Both outpatients and inpateints attending the STD Department for treatment of opportunistic infection of HIV – AIDS were included in the study. Five grams of formed or about 10 ml of unformed stool was collected and sample were examined within one to two hours of collection. The smears were prepared from stool samples and stained by modified Ziehel‑Neelsen. The results of the study are analaysed by using SPSS version 16.

Results: Out of the total 100 patients who were screened for cryptosporidium 37 were shown postive for it. Out of 68 males 28 (41.1%) were found to be postive for cryptospodia and out of 32 females 9(28.1%) were found to be postive. So compared to females the males were more affected and that was found to be statistically significant. Patients with CD4 amount < 200 were found to be more affected by cryptosporidium than patients with CD4 count more than 200 and this difference was found to be statistically significant. Conclusion: Given the severity and lack of effective specific trreatment of cryptosporidium in AIDS patients, emphasis should be given to its prevention and control.

Keywords: HIV/AIDS, Cryptosporidium, CD4 counts

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Editor in Chief of NJBMS Dr.Deepti Shastri, Professor and Head, Department of Anatomy, Academic Co-ordinator for Pre and Paraclinical Sciences, VMKV Medical College & Hospital, Salem.


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