UA-22728437-71


NJBMS - Volume 3, Issue 1, July - September 2012

Pages: 57-60

DENGUE: SEROPREVALENCE, COMPARISON OF RAPID TEST WITH ELISA

Author: JAYASIMHA V.L, THIPPESWAMY M.T.R, YOGESH BABU K.V, VINODKUMAR C.S, NIRANJAN H.P, RAGHUKUMAR K.G6, BASAVARAJAPPA K.G.

Category: Microbiology

[Download PDF]

Abstract:

Introduction: - Dengue is a major health problem in many parts of the tropical world. It is a mosquito borne illness caused by one of the serotypes of dengue viruses.

Aims and objectives: - The present study was done to know the common clinical features and Seroprevalence of dengue in our region. An attempt was made to compare rapid test SD dengue duo (IgM, IgG & NS-1 Ag detection) with capture ELISA (IgM, IgG Microlisa Dengue).

Materials & Methods: - 226 serum samples were tested in patients clinically suspected Dengue. All the 226 samples were subjected to IgG, IgM Microlisa test. The same were put on rapid SD bioline Dengue duo rapid test and was compared with ELISA.

Results:- 226 serum samples were tested in patients clinically suspected Dengue before noting common clinical signs and symptoms. 150 samples were tested positive with ELISA (either positive for IgG, IgM or both). Seroprevalence of 66% were reported. When compared with ELISA, Rapid test showed sensitivity of 80.6% specificity and positive predictive value of 100% & zero false positive rates. Efficiency of the test was 87.16%

Conclusion:- High prevalence rate in our region particularly in premonsoon & monsoon season gives an alarm to the doctors regarding early and accurate diagnosis of dengue virus infection. SD Dengue duo rapid test should be a valuable screening test for dengue fever which can be interpreted easily. Results were comparable to ELISA. It provides additional diagnostic investigation that compliments NS-1 antigen detection.

Keywords: Dengue, ELISA, rapid test, NS-1 antigen

No. of online users: 57

Search Articles



Visitor Counter

World wide visitors

News

Editor in Chief of NJBMS Dr.Deepti Shastri, Professor and Head, Department of Anatomy, Academic Co-ordinator for Pre and Paraclinical Sciences, VMKV Medical College & Hospital, Salem.


Indexed in

Index Copernicus (MCI recognized indexing body) ICV - 75.97, Scientific Indexing Services, Research Bib, Indian Science Publication, Eurasian Scientific Journal Index, Science Library Index, International Innovative Journal Impact Factor, Cite Factor, International Impact Factor Service,

Publication Statistics

Articles Statistics

Advertisements

Society for Basic Medical Sciences
NJBMS Journal - Indexed in Index Copernicus

Manuscript Statistics

Subscribe for TOC Alerts

Get the table of contents of current issues.

E-mail Alerts