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NJBMS - Volume 3, Issue 4, April - June 2013

Pages: 265-268

EFFECT OF GLYCEMIC CONTROL ON DIABETIC RETINOPATHY IN TYPE II DIABETES MELLITUS INDIVIDUALS

Author: P.NAVEEN, MRIGANKA BARUAH, S.VENKIDUSAMY

Category: Physiology

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Abstract:

Background:- Diabetic retinopathy is a major cause of blindness in population of working age. Chronic hyperglycemia is a major initiator of microvascular complications, poor glycemic control plays an important role in the development & progression of retinopathy. Aims:- This study is aimed to find the role of glycemic control on the presence of retinopathy in type II diabetics and the relationship between glycemic control and retinopathy.

Settings and Design:- Prospective randomised cross sectional study.

Material & Methods:- The study comprised of 90 subjects within the age group of 40-60 years who were classified into 3 groups of 30 subjects each, Group I: HbA1c < 7% - Controlled Diabetic Group, Group II: HbA1c > 7 % - Uncontrolled Diabetic Group and Group III: Control Group - HbA1c< 6%. Glycosylated Hemoglobin was investigated in diabetic subjects and control groups, Retinopathy was detected and graded into Non- proliferative diabetic retinopathy (NPDR) and Proliferative diabetic retinopathy (PDR).

Statistical Analysis used:- The results were statistically analyzed by One-way ANOVA and chi-square test between the groups.

Results:- Uncontrolled diabetics with poor glycemic control (HbA1c>7%) showed higher incidence of retinopathy (43.33%) when compared to controlled diabetics with good glycemic control (HbA1c< 7%) having retinopathy (10%).

Conclusion:-Uncontrolled hyperglycemia is associated with higher incidence of microvascular complication like retinopathy in diabetes. HbA1c is an indicator of long-term blood glucose concentrations. Diabetic retinopathy patients should be under periodic ophthalmological surveillance for prevention of blindness & other diabetes related complications by stringent glycemic control.

Keywords: Type II diabetes, glycemic control, retinopathy.

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Editor in Chief of NJBMS Dr.Deepti Shastri, Professor and Head, Department of Anatomy, Academic Co-ordinator for Pre and Paraclinical Sciences, VMKV Medical College & Hospital, Salem.


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