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NJBMS - Volume 3, Issue 2, October - December 2012

Pages: 141-144
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EPIDURAL ADMINISTRATION OF LOW – DOSE BUPIVACAINE WITH BUPRENORPHINE VS BUPIVACAINE WITH MORPHINE FOR POSTOPERATIVE ANA LGESIA IN THE CAESAREAN DELIVERY

Author: RAVI KANTH S.V., V. RAMARAO, PARIDA SHANTI LATHA, HARINATHBABU, P.REVATHI, JOSNA JOSE

Category: Clinical Sciences

Abstract:

Post operative pain after lower segment caesarean segment is almost always severe in nature and its makes very difficult for nursing mother to take care of baby. Its need early ambulation of caring mothers .This randomised double blind control study was carried out among 100 lower segment caesarean section (LSCS) patients, divided into two groups to assess the analgesic efficacy and side effects of epidural analgesia, group I with intermittent topup epidural bupivacaine (0.125%) with buprenorphine (0.060mg) N=50 and group II bupivacaine (0.125%) with morphine (1.5mg) N=50. Patients were under observation for 48 hours post operatively for onset, duration, potency of analgesia and its side effects. The demographic characteristics (age, weight and height) of the two groups were comparable and the differences among age, weight, were statistically significant and among height were not statistically significant. Postoperative pain score, blood pressure, heart rate, respiratory rate were measured at hourly during the first 48 h after operation. Both the drugs produced significant pain relief (assessed by vas scale). Onset of analgesia were earlier in group 1 and statastically significant. Duration of analgesia was statastically significant in group I with longer duration of action than morphine as in group II. The incidence of side effects was less in both groups and statastically not significant. Post operative analgesia was for longer duration in case of epidural buprenorphine than morphine.

Keywords: Post operative analgesia, epidural buprenorphine, morphine