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NJBMS - Volume 2, Issue 3, January - March 2012

Pages: 242-245
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ANTIMICROBIAL RESISTANCE PATTERN OF STAPHYLOCOCCUS AUREUS ISOLATED FROM CARRIERS EXPOSED AND NOT EXPOSED

TO HOSPITAL ENVIRONMENT

Author: Renushri B. V., Saha Avinandan, Nagraj E. R., Krishnamurthy Veena

Category: Microbiology

Abstract:

Aims: Staphylococcus aureus constitutes a considerable fraction of normal human microflora. This study evaluated the carriage of S. aureus in individuals exposed and not exposed to a hospital environment and compared their antimicrobial resistance patterns.

Materials and Methods: Swabs were collected from the nose, throat and web-spaces of 119 nursing students of the age group 18-23 years (exposed group) and 100 age matched pharmacy students (non-exposed group). S. aureus was identified phenotypically and antibiogram obtained as per Clinical and Laboratory Standards Institute (CLSI) guidelines.

Results: Resistance to penicillin, erythromycin, clindamycin, ciprofloxacin, cotrimoxazole and gentamicin were 77.2%,31.8%, 13.6%, 34.1%, 45.5% and 9.1%

respectively in the exposed group, and 83.3%, 22.2%, 11.1%,19.4%, 19.4% and 5.6% respectively in the non- exposed group. 40.9% and 11.1% S. aureus were methicillin resistant in the exposed and non-exposed groups respectively. Resistance to tetracycline was observed only in isolates from the non-exposed group. None of the isolates showed resistance to vancomycin, teicoplanin, netilmicin and linezolid in the two groups.

Conclusion: The results of this study could aid clinicians in considering appropriate options for empiric antimicrobial therapy for the treatment of both hospital and community acquired S. aureus infections.

Keywords: Staphylococcus aureus, Antibiogram of S. aureus, S. aureus carriers.