A RARE CASE OF GYNANDROBLASTOMA WITH JUVENILE GRANULOSA COMPONENT
Author: SRI VIDYA VVL, GAYATRI V.
Category: Pathology
Abstract:
We report a case of a female aged 20yrs, with complaint of Amenorrhea for 7months, which started with oligomenorrheic cycle of 2-3days / 2-3months for 2yrs. Clinically, it presents clinically as an abdominal mass, associated with either virilizing or feminizing manifestations. Histopathological study of adnexeal mass revealed characteristic features of juvenile granulosa cell tumor, associated with sertoli-leydig cell component. The tumor consisted of substantial amount of granulosa cell elements and sertoli cell elements, with intermingled leydig cells. Immunohistochemistry revealed the tumor cells in both granulosa cell and sertolileydig cell elements were positive for vimentin. The prognosis depends on the individual tumor components. We report this case in viewof its rarity.