2 billion people worldwide.[1] However, detection of microfilariae in pleural fluid is very rare.[2] Here, we report a case of disseminated tuberculosis with incidental detection of microfilariae of Wuchereria bancrofti in pleural fluid, blood smear, and cervical lymph node aspirate. A 45 year old male, farmer by occupation presented with chief complaints of back pain of 30 days duration. Fever, shortness of breath, pain abdomen for 1 week. Diagnosis of tuberculosis and filariasis were made based on radiological, biochemical and microbiological investigations and TB PCR. The patient was immunocompetant, negative for HIV infection.