Depression is the most common of all mood disorders. It has a neurobiological basis. Recently, vitamin D deficiency has been proposed as one of the contributors to the etiology of depression. Evidence has been favoring vitamin D deficiency as a causative reason for depression. Limitations in the studies that have been done so far warrant further research defining the role of vitamin D deficiency in depression. Management of depression in vitamin D deficiency consists of supplementation of the vitamin and antidepressants. Careful consideration should be done while choosing antidepressants as some of the antidepressants have been found to be associated with osteoporosis.
Keywords: Antidepressants, Depression, Supplementation, Vitamin D deficiency