HISTOMORPHOMETRIC STUDY OF DUCTUS ARTERIOSUS IN FETUSES OF DIFFERENT AGE GROUP
Author: MARY HYDRINA D'SILVA, RIJIED T SWER, J. ANBALAGAN, N.MUGUNTHAN, SUDHA RAO
Category: Anatomy
Abstract:
Ductus arteriosus (DA) from six fetuses of different gestational period (20-30 weeks) were studied microscopically to observe the gradual sequential changes that occur in the wall during the process of closure. DA was found to originate either from left pulmonary artery or from bifurcation of pulmonary trunk. Gradual increases in length, outer and inner diameter of DA were observed. Microscopically tunica media and tunica intima showed changes in the arrangement of muscle fibers, collagen and elastic fibrils. The appearance of intimal cushion due to the proliferation and migration of muscle fibers marked the occlusion process of lumen of DA.
