SEROPREVALENCE OF CHLAMYDIA TRACHOMATIS INFECTION IN
WOMEN WITH BAD OBSTETRIC HISTORY AND INFERTILITY
Author: MANJUNATH P. SALMANI , PREETI B. MINDOLLI G. VISHWANATH
Category: Microbiology
Abstract:
Chlamydia trachomatis has currently emerged as the most commonsexually transmitted pathogen. It is usually asymptomatic and is difficult to diagnose clinically. It is one of the causes for bad Obstetric History (BOH) and infertility. Women at highest risk often have the least access to health care facilities. Therefore there is a need for a rapid, simple, inexpensive and non-invasive test to detect C. trachomatis infection. Serological testing forms the mainstay of diagnosing the disease and to treat BOH and infertility. Hence the present study was conducted. Enzyme Linked Immunosorbent Assay (ELISA) was used for detection of IgG antibodies against C. trachomatis. Out of 130 cases, 65 had history of BOH, 40 had history of infertility and 25 healthy pregnant women (HPW) were used as controls. The seropositivity for C. trachomatis in the study was 25.4% (33). Out of 65 cases of BOH, seropositivity was 27.7% (18). Out of 40 cases of infertility, seropositivity was 35% (14) and out of 25 cases of HPW seropositivity was 4% (1). In BOH cases, women with history of two abortions showed seropositivity of 7.3% andwomen with history of three or more abortions showed seropositivity of 62.5%. Hence, seropositivity of C. trachomatis infection was found to be significant among women with BOHand infertility as compared toHPW.
Keywords: Chlamydia trachomatis; infertility; bad obstetric history; ELISA.
