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NJBMS - Volume 2, Issue 3, January - March 2012

Pages: 247-250
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BILIRUBIN AND URIC ACID - ARE THEY RISK FACTORS FOR CORONARY ARTERY DISEASE?

Author: C.K. Vijayasamundeeswari, J. Visalasree, T.S.Jesintha

Category: Biochemistry

Abstract:

Objectives: To investigate the role of serum uric acid, bilirubin levels in coronary artery disease (CAD).

Methods: 120 cases of coronary artery disease (CAD) patients having angiographic evidence of atherosclerosis were compared to 120 healthy controls for uric acid, total bilirubin and direct bilirubin in serum.

Results: Serum uric acid levels in patients with coronary artery disease was significantly higher in both men and women of CAD group (P <0.001). The Total bilirubin and Direct bilirubin levels of CAD group were significantly lower than the control group (P <0.001, p<0.001).

Conclusion: High serum uric acid level, low total bilirubin levels, low direct bilirubin levels in coronary artery disease are the risk factors for coronary artery disease.

Keywords: : Uric acid; bilirubin; coronary artery disease