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<Journal>
<PublisherName>njbms</PublisherName>
<JournalTitle>NJBMS</JournalTitle>
<PISSN>0976-6626</PISSN>
<EISSN>2455-1740</EISSN>
<Volume-Issue>Volume 11 Issue 4</Volume-Issue>
<PartNumber/>
<IssueTopic>Multidisciplinary</IssueTopic>
<IssueLanguage>English</IssueLanguage>
<Season>April - Jun 2021</Season>
<SpecialIssue>N</SpecialIssue>
<SupplementaryIssue>N</SupplementaryIssue>
<IssueOA>Y</IssueOA>
<PubDate>
<Year>2021</Year>
<Month>06</Month>
<Day>23</Day>
</PubDate>
<ArticleType>Physiology</ArticleType>
<ArticleTitle>BLOOD PRESSURE RESPONSE TO SUSTAINED HANDGRIP TEST – A SINGLE TEST FOR DIAGNOSING AUTONOMIC NEUROPATHY IN PATIENTS OF CHRONIC KIDNEY DISEASE ON HAEMODIALYSIS</ArticleTitle>
<SubTitle/>
<ArticleLanguage>English</ArticleLanguage>
<ArticleOA>Y</ArticleOA>
<FirstPage>247</FirstPage>
<LastPage>254</LastPage>
<AuthorList>
<Author>
<FirstName>Dr. T. Kiran</FirstName>
<LastName>Kumar1</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>Dr.</FirstName>
<LastName>A.L.Bajentri2</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
</Author>
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<DOI>10.31975/NJBMS.2021.11401</DOI>
<Abstract>Introduction: Cardiovascular autonomic dysfunction is a major complication of Chronic Kidney Disease (CKD) likely contributing to the high incidence of cardiovascular mortality in this patient population. The purpose of this study was to determine the frequency of autonomic neuropathy in patients with Chronic Kidney Disease on haemodialysis (HD) by using cardiovascular reflex tests.
Objectives: To assess the cardiovascular autonomic functions in patients of CKD on HD.
Methods: Following five tests were performed on 40 patients of CKD on HD
Parasympathetic function tests:
Heart-rate response to Valsalva manoeuvre.
Heart-rate variation during deep breathing.
Immediate heart-rate response to standing.
Sympathetic function tests:
Blood-pressure response to standing.
Blood-pressure response to sustained handgrip.
Results: Thirty two of forty subjects (80%) had one or more abnormal tests. Among five tests the two most abnormal tests were heart-rate variation during deep breathing(n=28 , 70%) and the blood pressure response to sustained hand grip(n=24,60%).
Conclusion: In this study 20 out of 24 subjects who had abnormal blood pressure response to sustained hand grip also had one or more abnormal parasympathetic test.So the blood pressure response to sustained hand grip test can alone be used to diagnose the autonomic neuropathy in patients of CKD on HD.</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>Chronic kidney disease; cardiovascular autonomic function tests; autonomic dysfunction; haemodialysis; isometric handgrip exercise</Keywords>
<URLs>
<Abstract>https://njbms.in/ubijournal-v1copy/journals/abstract.php?article_id=13416&title=BLOOD PRESSURE RESPONSE TO SUSTAINED HANDGRIP TEST – A SINGLE TEST FOR DIAGNOSING AUTONOMIC NEUROPATHY IN PATIENTS OF CHRONIC KIDNEY DISEASE ON HAEMODIALYSIS</Abstract>
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<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
<ReferencesfirstPage>16</ReferencesfirstPage>
<ReferenceslastPage>19</ReferenceslastPage>
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</References>
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