<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
<ArticleSet>
  <Article>
    <Journal>
      <PublisherName>njbms</PublisherName>
      <JournalTitle>NJBMS</JournalTitle>
      <PISSN>0976-6626</PISSN>
      <EISSN>2455-1740</EISSN>
      <Volume-Issue>Volume 6, Issue 4</Volume-Issue>
      <PartNumber/>
      <IssueTopic>Multidisciplinary</IssueTopic>
      <IssueLanguage>English</IssueLanguage>
      <Season>April - June 2016</Season>
      <SpecialIssue>N</SpecialIssue>
      <SupplementaryIssue>N</SupplementaryIssue>
      <IssueOA>Y</IssueOA>
      <PubDate>
        <Year>-0001</Year>
        <Month>11</Month>
        <Day>30</Day>
      </PubDate>
      <ArticleType>Biochemistry</ArticleType>
      <ArticleTitle>ANALYTICAL SENSITIVITY OF TSH ASSAYS BY ELISA AND ELFA</ArticleTitle>
      <SubTitle/>
      <ArticleLanguage>English</ArticleLanguage>
      <ArticleOA>Y</ArticleOA>
      <FirstPage>157</FirstPage>
      <LastPage>162</LastPage>
      <AuthorList>
        <Author>
          <FirstName>K.PRAMILA</FirstName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>N</CorrespondingAuthor>
          <ORCID/>
          <FirstName>POONGUZHALI</FirstName>
          <LastName>GOPINATH</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>K.MENAKA</FirstName>
          <LastName>SHANTHI</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>M.DIVYA</FirstName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
        </Author>
      </AuthorList>
      <DOI/>
      <Abstract>INTRODUCTION : The technological advances from radioimmunoassay to immunometric assays have greatly enhanced the sensitivity of TSH assays over the last three decades and has firmly established TSH as the single most reliable Thyroid function test in assessing the Thyroid hormone status of an individual.AIMS AND OBJECTIVE : The objective of this current study is to compare the performance of TSH assay based on Enzyme Linked Fluorescent Assay (VIDAS system) with Enzyme Linked Immunosorbant assay technology (Accubind) and also to compare the analytical sensitivity of the TSH assay by the above two technologies.MATERIALS AND METHODS : Thyroid stimulating hormone levels have been assayed in the serum of 105 patients by both ELISA and ELFA so as to analyze the performance of the above two technologies. The term analytical sensitivity refers to a minimal concentration of TSH that can be detected by an assay with greater confidence.RESULTS : There exists statistically significant difference between assays by ELISA and ELFA in Euthyroid (p</Abstract>
      <AbstractLanguage>English</AbstractLanguage>
      <Keywords>ELISA, ELFA, Thyroid stimulating hormone, analytical sensitivity</Keywords>
      <URLs>
        <Abstract>https://njbms.in/ubijournal-v1copy/journals/abstract.php?article_id=1563&amp;title=ANALYTICAL SENSITIVITY OF TSH ASSAYS BY ELISA AND ELFA</Abstract>
      </URLs>
      <References>
        <ReferencesarticleTitle>References</ReferencesarticleTitle>
        <ReferencesfirstPage>16</ReferencesfirstPage>
        <ReferenceslastPage>19</ReferenceslastPage>
        <References/>
      </References>
    </Journal>
  </Article>
</ArticleSet>