<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>njbms</PublisherName> <JournalTitle>NJBMS</JournalTitle> <PISSN>0976-6626</PISSN> <EISSN>2455-1740</EISSN> <Volume-Issue>Volume 3, Issue 2</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>October - December 2012</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Physiology</ArticleType> <ArticleTitle>VARIATIONS IN LEVELS OF GAMMA GLUTAMYL TRANSFERASE AND GLUTATHIONE PEROXIDASE DURING PREGNANCY ADVANCEMENT AND PREECLAMPSIA</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>130</FirstPage> <LastPage>133</LastPage> <AuthorList> <Author> <FirstName>JAYASHREE P.</FirstName> <LastName>ANDHARE</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>MADHUR M</FirstName> <LastName>GUPTA</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>MANJU S</FirstName> <LastName>CHANDANKHEDE</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>SHEELA</FirstName> <LastName>JAIN</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Background : Oxidative stress is known to be a key factor associated with preeclampsia. Glutathione Peroxidase(GPx), an antioxidant enzyme along with cellular γ -Glutamyl transferase (GGT) is responsible for protecting cells from damage due to free radicals like hydrogen and lipid peroxides.Aim : To assess prooxidant and antioxidant GGT and GPx in pregnancy and preeclampsia.Design : A case control study.Material and methods: Estimation of malondialdehyde, GGT and GPx level in blood was carried out by chemical and enzymatic kit method in 20 non-pregnant women as controls, 20 pregnant women in first week of each trimester and 20 preeclampsia patients.Statistical analysis: Done by `t` test.Results and conclusion: Serum GGT though not significant increased in first trimester was found to be towards the upper limit of normal range in pregnant women and raised above normal in preeclampsia patients(p</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Preeclampsia, Oxidative stress, Glutathione Peroxidase, Gamma glutamyl transferase, Antioxidant</Keywords> <URLs> <Abstract>https://njbms.in/ubijournal-v1copy/journals/abstract.php?article_id=1629&title=VARIATIONS IN LEVELS OF GAMMA GLUTAMYL TRANSFERASE AND GLUTATHIONE PEROXIDASE DURING PREGNANCY ADVANCEMENT AND PREECLAMPSIA</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References/> </References> </Journal> </Article> </ArticleSet>